Examination of the working memory components in normal aging and in dementia of the Alzheimer type.
نویسندگان
چکیده
The verbal and attentional components of working memory were examined in patients with Alzheimer's disease, normal elderlies, and young controls. Patients with Alzheimer's disease, showed a reduced span but were sensitive to word length. This is indicative of a functional rehearsal procedure. However, the effect of phonological similarity on immediate recall was smaller in patients with Alzheimer's disease and these patients showed a depressed performance in tasks of phonological analysis. There was also a significant decrement in a task that assessed the attentional component of working memory. Examination of individual patterns of performance showed that the phonological deficiency was severe in a subgroup of patients while the attentional deficit was more general.
منابع مشابه
Effect of the Xenograft Transplantation of Human Dental Pulp Stem Cells on Anxiety and Memory in Trimethyltin Induced-Alzheimer Disease Model
Background and Objectives: Alzheimer's disease (AD) is a neurodegenerative disease and the most common cause of dementia. The characteristics of this disease are amnesia, cognitive and verbal disorders, memory deficit, paranoia, depression, and anxiety. In this study, the alterations of cognitive-behavioral and nuclear factor kappa (NF-κ) factor, were investigated following the xenogenic transp...
متن کاملThe Effect of Dual Task Interference on Gait in Aging: Role of Working Memory Components
The purpose of the present study was to investigate the effect of concurrent cognitive tasks activating phonological loop and visuospatial scratchpad of working memory on gait in older adults.12 older adults with the age range of 65-70 years performed walking trials in 3 counterbalanced testing conditions including single walking, walking while performing visuospatial task and walking while per...
متن کاملO 18: Autoimmune Dementia
Dementia is defined as significant acquired cognitive impairment in one or more cognitive domains that represents a significant decline from previous baseline and interferes with independence in daily activities. Autoimmune dementia is a term that has been used to describe a steroid-responsive autoimmune disorder characterized by a rapidly progressive dementia with a fluctuating course. Even co...
متن کاملComparison of visual evoked potential changes in patients with alzheimer, vascular dementia and minimal cognitive Impairment with healthy people: a case-control study
Background: Alzheimer dementia as the most common cause of dementia is a chronic, progressive, irreversible and incurable disease. The second most common cause of dementia after Alzheimer is vascular dementia. One of the systems involved in dementia is the visuospatial system and visual evoked potential (VEP) can be one of the diagnostic methods for this disease. Therefore, the present study ai...
متن کاملP 26: The Protective Effect of Nano-Hesperetin on Memory Disorder Induced by Streptozotocinin Male Rat in Alzheimer Models
Introduction: Intracerebroventricular (i.c.v.) injection of streptozotocin (STZ) to rodents has been reported as an appropriate model for sporadic dementia of Alzheimer's type (SDAT), characterized by a progressive impairment of memory. However, very little or nothing is known about non-cognitive behavioral effects in the STZ model. This study was carried out in order to show the protective eff...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Neuropsychologia
دوره 34 3 شماره
صفحات -
تاریخ انتشار 1996